发明授权
- 专利标题: Method of treating depression with certain triazine derivatives
- 专利标题(中): 用某些三嗪衍生物治疗抑郁症的方法
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申请号: US424397申请日: 1995-04-25
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公开(公告)号: US5789407A公开(公告)日: 1998-08-04
- 发明人: Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Shigeto Kitamura , Shunji Ichikawa , Joji Nakamura , Shizuo Shiozaki
- 申请人: Fumio Suzuki , Nobuaki Koike , Junichi Shimada , Shigeto Kitamura , Shunji Ichikawa , Joji Nakamura , Shizuo Shiozaki
- 申请人地址: JPX Tokyo
- 专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX5-221431 19930906
- 主分类号: A61K31/53
- IPC分类号: A61K31/53 ; C07D487/04 ; A61K31/535
摘要:
The present invention relates to an antidepressant containing as an active ingredient a triazine derivative or a pharmaceutically acceptable salt thereof, the derivative being represented by the following Formula (I): ##STR1## in which, R.sup.1 represents hydrogen, substituted or unsubstituted lower alkyl, or substituted or unsubstituted lower alkanoyl; R.sup.2 represents hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, or a substituted or unsubstituted heterocyclic group; R.sup.3 represents a substituted or unsubstituted heterocyclic group; X represents a single bond, O, S, S(O), S(O).sub.2, or NR.sup.4 (in which R.sup.4 represents hydrogen, or substituted or unsubstituted lower alkyl; or R.sup.2 and NR.sup.4 are combined to form a substituted or unsubstituted 4 to 6-membered saturated heterocyclic group); and A represents N or CR.sup.5 (in which R.sup.5 represents hydrogen, or substituted or unsubstituted lower alkyl).