发明授权
- 专利标题: Peptides from mammalian pancreatic cholesterol esterase
- 专利标题(中): 来自哺乳动物胰胆固醇酯酶的肽
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申请号: US461881申请日: 1995-06-05
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公开(公告)号: US5792832A公开(公告)日: 1998-08-11
- 发明人: Louis George Lange, III , Curtis A. Spilburg
- 申请人: Louis George Lange, III , Curtis A. Spilburg
- 专利权人: Lange, Iii; Louis George,Spilburg; Curtis A.
- 当前专利权人: Lange, Iii; Louis George,Spilburg; Curtis A.
- 主分类号: A23L5/20
- IPC分类号: A23L5/20 ; A61K39/00 ; C07K7/06 ; C07K16/40 ; C12N9/18 ; C12N15/55 ; C12P7/64 ; C12P33/00 ; C12Q1/68 ; C07K9/00 ; C12N9/16
摘要:
The invention provides methods for the purification to homogeneity of pancreatic cholesterol esterase in useful quantities from a variety of mammalian species. The gene for a mammalian pancreatic cholesterol esterase has been cloned and sequenced, and is useful for expressing cholesterol esterase in a transformed eukaryotic or prokaryotic cell culture. Thus, methods according to the invention enable the production of large quantities of pancreatic cholesterol esterase for the screening of inhibitors, the production of antibodies, and for commercial purposes related to the alteration of cholesterol/cholesterol ester composition of materials containing free or esterified cholesterol.
公开/授权文献
- US5304786A High density two-dimensional bar code symbol 公开/授权日:1994-04-19
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