发明授权
- 专利标题： Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides
- 专利标题（中）： 天然环糊精及其衍生物用于溶解银杏内酯类抗血小板聚集剂
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申请号： US711265申请日： 1996-09-09
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公开(公告)号： US5798342A公开(公告)日： 1998-08-25
- 发明人: Jacques Defaye , Valerie Laine , Florence Djedaini-Pilard , Bruno Perly
- 申请人： Jacques Defaye , Valerie Laine , Florence Djedaini-Pilard , Bruno Perly
- 申请人地址： FRX Paris
- 专利权人： Commissariat a l'Energie Atomique
- 当前专利权人： Commissariat a l'Energie Atomique
- 当前专利权人地址： FRX Paris
- 优先权： FRX9511040 19950920
- 主分类号： C07D493/22
- IPC分类号： C07D493/22 ; A61K31/365 ; A61K36/00 ; A61K36/16 ; A61K47/40 ; A61K47/48 ; A61P7/02 ; A61P43/00 ; C08B37/00 ; C08B37/16 ; A61K31/715 ; A61K31/335
摘要：
The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides. The cyclodextrins used comply with the formula: ##STR1## in which n is equal to 6, 7 or 8 and the R.sup.1, which can be the same or different, represent OH or SR.sup.2 with R.sup.2 representing a group derived from a monosaccharide or an oligosaccharide. The Ginkgolide is preferably Ginkgolide B.
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