发明授权
US5801254A Arteminolide derivatives and process for the manufacture thereof
失效
Arteminolide衍生物及其制备方法
- 专利标题： Arteminolide derivatives and process for the manufacture thereof
- 专利标题（中）： Arteminolide衍生物及其制备方法
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申请号： US906612申请日： 1997-08-05
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公开(公告)号： US5801254A公开(公告)日： 1998-09-01
- 发明人: Byoung-Mog Kwon , Song-Hae Bok , Seung-Ho Lee , Young-Kook Kim , Mi-Jeong Kim , Jongheon Shin , Youngwan Seo , Soo-Ik Chang
- 申请人： Byoung-Mog Kwon , Song-Hae Bok , Seung-Ho Lee , Young-Kook Kim , Mi-Jeong Kim , Jongheon Shin , Youngwan Seo , Soo-Ik Chang
- 申请人地址： KRX Seoul
- 专利权人： Korea Institute of Science and Technology
- 当前专利权人： Korea Institute of Science and Technology
- 当前专利权人地址： KRX Seoul
- 优先权： KRX96-32714 19960806; KRX97-8517 19970313
- 主分类号： C07D493/10
- IPC分类号： C07D493/10 ; C07D307/94
摘要：
Arteminolides obtained from Artemisia sylvatica MAXIMOWICZ and having a core structure of formula (I) or an isomeric structure thereof are effective farnesyl-protein transferase inhibitors as well as angiogenesis suppressors, and, accordingly, they are useful for the treatment of various cancers and angiogenesis-related diseases. ##STR1##
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