An operational amplifier frequency self-compensated with respect to closed-loop gain comprises a transconductance input stage and an amplifier output stage connected serially together to receive an input signal on at least one input terminal of the amplifier and generate an amplified signal on an output terminal of the amplifier. Provided between the input and output stages is an intermediate node which is connected to a compensation block to receive a frequency-variable compensation signal therefrom. The compensation block is coupled with its input to the input terminal of the amplifier The compensation block is connected to receive at least the feedback signal. Preferably, the compensation signal is variable as a function of a gain value which is determined by the feedback circuit, and said variation of the compensation signal occurs in a relationship of inverse proportionality to the gain value.