发明授权
US5840991A Antiatherosclerosis agents for lipid-lowering and antiperoxidative
activity
失效
用于降脂和抗过氧化活性的抗动脉粥样硬化剂
- 专利标题: Antiatherosclerosis agents for lipid-lowering and antiperoxidative activity
- 专利标题(中): 用于降脂和抗过氧化活性的抗动脉粥样硬化剂
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申请号: US932030申请日: 1997-09-17
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公开(公告)号: US5840991A公开(公告)日: 1998-11-24
- 发明人: Feng-Wen Yeng , Shan-Shue Wang , Jaw-Yuh Chiu , Chin-Fen Lee , Chia-Lin J. Wang
- 申请人: Feng-Wen Yeng , Shan-Shue Wang , Jaw-Yuh Chiu , Chin-Fen Lee , Chia-Lin J. Wang
- 申请人地址: TWX Taipei
- 专利权人: Development Center for Biotechnology
- 当前专利权人: Development Center for Biotechnology
- 当前专利权人地址: TWX Taipei
- 主分类号: A61K31/10
- IPC分类号: A61K31/10 ; A61P3/06 ; A61P9/10 ; C07C315/02 ; C07C317/22 ; C07C319/14 ; C07C323/20 ; C07L315/00 ; A01N41/10
摘要:
The invention relates to novel compounds of formula (I) ##STR1## wherein R.sub.1 represents hydrogen, hydroxy or alkoxy; R.sub.2, R.sub.3, R.sub.4 and R.sub.5 may be hydrogen or alkyl; and n is 0,1 or 2; and the pharmaceutically acceptable salts thereof. The invention also relates to the processes for preparing the compounds of formula (I), and the pharmaceutical compositions containing them, and their use as a low density lipoprotein peroxidation inhibitors, anti-atherosclerotic agents and/or antihyperlipidemic agents.
公开/授权文献
- USD346331S Fluid-dispensing container 公开/授权日:1994-04-26
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