Invention Grant
US5843956A Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo (3,4-b)
quinolin-4-amines and compositions and methods of use thereof
失效
取代的N-芳基甲基和杂环基甲基-1H-吡唑并（3,4-b）喹啉-4-胺及其组合物及其使用方法
- Patent Title: Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo (3,4-b) quinolin-4-amines and compositions and methods of use thereof
- Patent Title (中): 取代的N-芳基甲基和杂环基甲基-1H-吡唑并（3,4-b）喹啉-4-胺及其组合物及其使用方法
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Application No.: US801679Application Date: 1997-02-18
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Publication No.: US5843956APublication Date: 1998-12-01
- Inventor: Virendra Kumar , John Alan Dority, Jr.
- Applicant: Virendra Kumar , John Alan Dority, Jr.
- Applicant Address: FRX Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FRX Paris
- Main IPC: A61K31/435
- IPC: A61K31/435 ; A61K31/4745 ; A61P9/00 ; A61P9/12 ; C07D471/04 ; A61K31/47 ; A61K31/495 ; C07D215/46
Abstract:
Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo�3,4-b!quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing or reducing nitrate-induced tolerance and d) treating angina pectoris, congestive heart disease and myocardial infarction utilizing them.
Public/Granted literature
- US5306475A Reactive calcium hydroxides Public/Granted day:1994-04-26
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