发明授权
- 专利标题： Synthetic triple helix-forming compound precursors
- 专利标题（中）： 合成的三螺旋形成化合物前体
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申请号： US384324申请日： 1995-02-01
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公开(公告)号： US5844110A公开(公告)日： 1998-12-01
- 发明人: Barry I. Gold
- 申请人： Barry I. Gold
- 申请人地址： NE Omaha
- 专利权人： University of Nebraska Board of Regents
- 当前专利权人： University of Nebraska Board of Regents
- 当前专利权人地址： NE Omaha
- 主分类号： C07D239/84
- IPC分类号： C07D239/84 ; C07D403/04 ; C07H21/00 ; C12N15/113 ; C07H7/06 ; C07D239/72 ; C07D471/00 ; C07D487/00
摘要：
The present invention discloses novel monomeric compositions which are substituted quinoline- or quinazoline-based structures capable of hydrogen bonding specifically with interstrand purine-pyrimidine base pairs in a double-stranded Watson-Crick DNA molecule. Furthermore, the novel monomeric compounds of the present invention are capable of being assembled in specific sequences into oligomers capable of binding with sequence specificity to duplex DNA via a triple helix motif.
公开/授权文献
- US4414201A Immunopotentiator containing abrin 公开/授权日：1983-11-08
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