发明授权
- 专利标题： Fused pyridazine compounds
- 专利标题（中）： 稠合哒嗪化合物
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申请号： US619621申请日： 1996-04-09
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公开(公告)号： US5849741A公开(公告)日： 1998-12-15
- 发明人: Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
- 申请人： Nobuhisa Watanabe , Yasuhiro Kabasawa , Yasutaka Takase , Fumihiro Ozaki , Keiji Ishibashi , Kazuki Miyazaki , Masayuki Matsukura , Shigeru Souda , Kazutoshi Miyake , Hiroki Ishihara , Kohtaro Kodama , Hideyuki Adachi
- 申请人地址： JPX Tokyo
- 专利权人： Eisai Co., Ltd.
- 当前专利权人： Eisai Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX6-187128 19940809; JPX6-316337 19941220
- 主分类号： C07D237/34
- IPC分类号： C07D237/34 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/12 ; C07D405/12 ; C07D405/14 ; C07D471/04 ; C07D521/00 ; A01K31/50 ; C07D237/30
摘要：
A fused pyridazine compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof which exhibits an inhibitory activity against cyclic GMP phosphodiesterase (hereinafter referred to as "cGMP-PDE"). The compounds are useful as preventive and therapeutic agents for diseases for which a cGMP-PDE inhibiting action is efficacious, for example, ischemic heart diseases such as angina pectoris, myocardial infarct and chronic and acute cardiac failure, pulmonary hypertension, arteriosclerosis and bronchial asthma. ##STR1##
公开/授权文献
- US5095758A Water cut monitoring means and method 公开/授权日：1992-03-17