发明授权
- 专利标题: Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials
- 专利标题(中): 被双环氨基取代的吡啶酮羧酸衍生物作为抗菌剂
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申请号: US875678申请日: 1997-08-04
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公开(公告)号: US5849757A公开(公告)日: 1998-12-15
- 发明人: Makoto Takemura , Youichi Kimura , Katsuhiro Kawakami , Kenichi Kimura , Hitoshi Ohki , Norikazu Matsuhashi , Haruko Kawato
- 申请人: Makoto Takemura , Youichi Kimura , Katsuhiro Kawakami , Kenichi Kimura , Hitoshi Ohki , Norikazu Matsuhashi , Haruko Kawato
- 申请人地址: JPX Tokyo
- 专利权人: Daiichi Pharmaceutical Co., Ltd.
- 当前专利权人: Daiichi Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX7-015614 19950202; JPX7-019478 19950207; JPX7-019481 19950207
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; A61K31/435 ; A61K31/47 ; C07D471/04
摘要:
This invention relates to a N.sub.1 -(halogenocyclopropyl)-substituted pyridonecarboxylic acid derivative represented by the following formula (I): ##STR1## wherein X.sup.1 is a halogen atom or a hydrogen atom; X.sup.2 is a halogen atom; R.sup.1 is a hydrogen atom, a hydroxyl group, a thiol group, a halogenomethyl group, an amino group, an alkyl group or an alkoxy group which may have a substituent group; R.sup.2 is a group represented by the following formula (II): ##STR2## wherein R.sup.3 and R.sup.4 are independently a hydrogen atom or an alkyl group and n is an integer of 1 or 2; A is a nitrogen atom or a partial structure of the following formula (III): ##STR3## wherein X.sup.3 is a hydrogen atom, a halogen atom, a cyano group, an amino group, an alkyl group, a halogenomethyl group, an alkoxyl group or a halogenomethoxyl group which may have a substituent group; and R is a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxycarbonyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidynyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, a 3-acetoxy-2-oxobutyl group, an alkyl group, an alkoxymethyl group or a phenylalkyl group, and provides a heterocyclic compound useful as antibacterial drugs.
公开/授权文献
- US5467477A Antenna and tuner combination 公开/授权日:1995-11-14
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