发明授权
- 专利标题： Mammaglobin, a mammary-specific breast cancer protein
- 专利标题（中）： 乳腺珠蛋白，乳腺特异性乳腺癌蛋白
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申请号： US722304申请日： 1996-09-30
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公开(公告)号： US5855889A公开(公告)日： 1999-01-05
- 发明人: Mark A. Watson , Timothy P. Fleming
- 申请人： Mark A. Watson , Timothy P. Fleming
- 申请人地址： MO St. Louis
- 专利权人： Washington University
- 当前专利权人： Washington University
- 当前专利权人地址： MO St. Louis
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; C07H21/04 ; C07K14/47 ; C07K14/82 ; C07K16/32 ; C12P21/08 ; C12Q1/68 ; G01N33/574 ; G01N33/53 ; C07K7/06 ; C07K14/435
摘要：
A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.
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