发明授权
US5856350A 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as
antidepressants
失效
3-苯基-1,4-二烷基-1,2,4-三唑鎓盐及其作为抗抑郁药的用途
- 专利标题: 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants
- 专利标题(中): 3-苯基-1,4-二烷基-1,2,4-三唑鎓盐及其作为抗抑郁药的用途
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申请号: US764964申请日: 1996-12-13
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公开(公告)号: US5856350A公开(公告)日: 1999-01-05
- 发明人: Christopher Robin Dalton , John Michael Kane , John Herr Kehne
- 申请人: Christopher Robin Dalton , John Michael Kane , John Herr Kehne
- 申请人地址: OH Cincinnati
- 专利权人: Hoechst Marion Roussel, Inc.
- 当前专利权人: Hoechst Marion Roussel, Inc.
- 当前专利权人地址: OH Cincinnati
- 主分类号: A61K31/41
- IPC分类号: A61K31/41 ; A61P25/24 ; A61P25/26 ; C07D249/08 ; A01N43/653
摘要:
This invention relates to the treatment of depression by administration of novel 3-(R.sub.n -phenyl)-1,4-dialkyl-1,2,4-triazolium salts of the formula ##STR1## wherein R is halogen, trifluoromethyl, C.sub.1-4 lower alkyl or C.sub.1-4 lower alkoxy,n is zero, 1 or 2, andR.sub.1 and R.sub.4 independently represent C.sub.1-3 lower alkyl;and A.sup.- represents a pharmaceutically acceptable anion.
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