发明授权
US5856574A Ortho-subsituted benzoylguanidines, process for their preparation, their
use as a medicament or diagnostic, and medicament containing them
失效
邻苯甲酰胍，其制备方法，它们作为药物或诊断剂的用途以及含有它们的药物
- 专利标题： Ortho-subsituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
- 专利标题（中）： 邻苯甲酰胍，其制备方法，它们作为药物或诊断剂的用途以及含有它们的药物
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申请号： US804023申请日： 1997-02-21
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公开(公告)号： US5856574A公开(公告)日： 1999-01-05
- 发明人: Andreas Weichert , Joachim Brendel , Heinz-Werner Kleemann , Hans Jochen Lang , Jan-Robert Schwark , Udo Albus , Wolfgang Scholz
- 申请人： Andreas Weichert , Joachim Brendel , Heinz-Werner Kleemann , Hans Jochen Lang , Jan-Robert Schwark , Udo Albus , Wolfgang Scholz
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX19606509.7 19960222
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61K31/155 ; A61P1/16 ; A61P9/00 ; A61P9/06 ; A61P9/08 ; A61P9/10 ; A61P13/02 ; A61P15/00 ; A61P35/00 ; A61P43/00 ; C07C279/10 ; C07C279/20 ; C07C279/22 ; C07C233/00
摘要：
Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing themOrtho-substituted benzoylguanidines of the formula I ##STR1## in which R(2) and R(3) have the meanings given in the claims, are suitable, as antiarrhythmic pharmaceuticals having a cardioprotective component, for the prophylaxis and treatment of infarction and for the treatment of angina pectoris. They also inhibit, in a preventive manner, the pathophysiological processes associated with the development of ischemically induced damage, in particular in association with the triggering of ischemically induced cardiac arrhythmias.
公开/授权文献
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