发明授权
US5858708A Polynucleotides encoding two novel human neuroendocrine-specific proteins
失效
编码两种新型人神经内分泌特异性蛋白的多核苷酸
- 专利标题： Polynucleotides encoding two novel human neuroendocrine-specific proteins
- 专利标题（中）： 编码两种新型人神经内分泌特异性蛋白的多核苷酸
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申请号： US700607申请日： 1996-08-12
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公开(公告)号： US5858708A公开(公告)日： 1999-01-12
- 发明人: Olga Bandman , Janice Au-Young , Surya K. Goli , Jennifer L. Hillman
- 申请人： Olga Bandman , Janice Au-Young , Surya K. Goli , Jennifer L. Hillman
- 专利权人： Bandman; Olga,Au-Young; Janice,Goli; Surya K.,Hillman; Jennifer L.
- 当前专利权人： Bandman; Olga,Au-Young; Janice,Goli; Surya K.,Hillman; Jennifer L.
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/00 ; A61K39/395 ; A61K45/00 ; A61K48/00 ; A61P25/28 ; A61P35/00 ; C07K14/47 ; C07K16/18 ; C07K16/28 ; C12N1/21 ; C12N15/09 ; C12N15/12 ; C12P21/08 ; C12N15/85
摘要：
The present invention provides polynucleotides which identify and encode two novel human NSP-like proteins (NSPLP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NSPLP. The invention also provides for the use of substantially purified NSPLP, antagonists, and in pharmaceutical compositions for the treatment of diseases associated with the expression of NSPLP. Additionally, the invention provides for the use of antisense molecules to NSPLP in pharmaceutical compositions for treatment of diseases associated with the expression of NSPLP. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of polynucleotides encoding NSPLP or anti-NSPLP antibodies which specifically bind to NSPLP.
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