发明授权
- 专利标题: Method to prevent transplant rejection
- 专利标题(中): 防止移植排斥的方法
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申请号: US759318申请日: 1996-12-02
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公开(公告)号: US5882328A公开(公告)日: 1999-03-16
- 发明人: Julia G. Levy , Modestus O. K. Obochi
- 申请人: Julia G. Levy , Modestus O. K. Obochi
- 申请人地址: CAX Vancouver
- 专利权人: QLT Phototherapeutics, Inc.
- 当前专利权人: QLT Phototherapeutics, Inc.
- 当前专利权人地址: CAX Vancouver
- 主分类号: C07D487/22
- IPC分类号: C07D487/22 ; A61K41/00 ; A61K45/00 ; A61P37/06 ; A61N1/30 ; A61M31/00
摘要:
Donor tissue containing antigen-presenting cells (APCs) can be modified to reduce rejection when the donor tissue is used as an allograft by exposing the donor tissue which has been treated with a photosensitizing agent having an absorption maximum between 400-900 nm to a wavelength absorbed by the photosensitizing agent so as to attenuate the APCs in the donor tissue but wherein the light is not cytotoxic to the APCs.
公开/授权文献
- US5213529A Oar horn 公开/授权日:1993-05-25
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