发明授权
- 专利标题： Antigenic peptide compound and immunoassay
- 专利标题（中）： 抗原肽化合物和免疫测定法
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申请号： US617929申请日： 1996-04-24
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公开(公告)号： US5885771A公开(公告)日： 1999-03-23
- 发明人: Toshiaki Kumazawa
- 申请人： Toshiaki Kumazawa
- 申请人地址： JPX Tokyo
- 专利权人： SRL, Inc.
- 当前专利权人： SRL, Inc.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX5-272864 19931029; JPX6-207695 19940831
- 主分类号： C07K14/18
- IPC分类号： C07K14/18 ; C12Q1/70 ; A61K39/29 ; A61K39/295 ; G01N33/569
摘要：
An HCV antibody contained in a specimen is measured by an immunoassay method by utilizing the specific binding affinity of a hepatitis C virus (HCV) antibody to an antigenic peptide having the amino acid sequence represented by the following formula (1) or (2):Leu-Ser-Gly-Arg-Pro-Ala-Ile-Val-Pro-Asp-Arg-Glu-Val-Leu-Tyr-Gln-Glu-Phe-Asp-Glu . . . (SEQ ID NO: 1)Val-Asn-Gln-Arg-Ala-Val-Val-Ala-Pro-Asp-Lys-Glu-Val-Leu-Tyr-Glu-Ala-Phe-Asp-Glu . . . (SEQ ID NO: 2)According to the above method, it is possible to determine the serotype of the specimen simply and accurately, while suppressing a cross reaction or a non-specific reaction. As a result, it is also possible to preliminarily predict the effect of interferon treatment in an accurate manner, and to simply observe the course of the curing or treatment for hepatitis C.
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