发明授权
- 专利标题： Dicarbonyl-containing compounds
- 专利标题（中）： 含二羰基化合物
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申请号： US588763申请日： 1996-01-19
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公开(公告)号： US5886046A公开(公告)日： 1999-03-23
- 发明人: Ralph F. Hirschmann , Amos B. Smith, III , Paul Sprengeler , Wenqing Yao , Paul Anderson
- 申请人： Ralph F. Hirschmann , Amos B. Smith, III , Paul Sprengeler , Wenqing Yao , Paul Anderson
- 申请人地址： PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： PA Philadelphia
- 主分类号： C07C235/36
- IPC分类号： C07C235/36 ; C07C237/20 ; C07C271/22 ; A61K31/165 ; C07C233/05
摘要：
This invention relates to chemical compounds that contain adjacent carbonyl groups, which effectively inhibit the biological, chemical, and/or physical properties of enzymes and other medicinally-significant proteins. In particular, the invention relates to dicarbonyl compounds that are capable of acting as enzyme inhibitors, including irreversible inhibitors of HIV-1 protease.
公开/授权文献
- US3996536A Metal-insulator-semiconductor device phase shifter 公开/授权日：1976-12-07
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