A connector system of use with ultrasound imaging probes is fully submersible in liquids and saturated steam at elevated temperatures and pressure. The system includes a submersible connector (32) for terminating a probe assembly (26) and a receptacle assembly (74) for mating the submersible connector (32) with an ultrasound imaging system (10). The submersible connector (32) includes a printed wiring board (34) having plated contact pads (48) on one surface and microcoaxial cable terminations (54) on the opposite side. A molded housing (36) encloses the microcoaxial cable terminations (54) and is bonded to the printed wiring board (34). The edges of the printed wiring board (34) are used to align the submersible connector (32) within the receptacle assembly (74). The molded housing (36) is narrowed in one dimension to make available a portion of the printed wiring board (34) for clamping in a locked position. Blind vias (68, 72) are used to connect the contact pads (48) and cable termination pads (54) through the printed wiring board (34), to prevent corrosive fluids and steam from entering the region protected by the molded housing (36). A preferred embodiment of a receptacle assembly (74) for electrically and mechanically mating with the submersible connector (32) includes a manually operated self guiding mechanism for receiving the submersible connector (32), aligning it with mating contacts (98) and locking the connector (32) into a mated position. The receptacle assembly (74) is easily operated by use of a handle (88) for rotating a cam (106) that actuates a movable slide (86).