发明授权
- 专利标题： Altered telomere repeat binding factor 2
- 专利标题（中）： 改变的端粒重复结合因子2
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申请号： US18628申请日： 1998-02-04
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公开(公告)号： US5917019A公开(公告)日： 1999-06-29
- 发明人: Titia de Lange , Bas Van Steensel , Alessandro Bianchi
- 申请人： Titia de Lange , Bas Van Steensel , Alessandro Bianchi
- 申请人地址： NY New York
- 专利权人： The Rockefeller University
- 当前专利权人： The Rockefeller University
- 当前专利权人地址： NY New York
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/47 ; C12N1/21 ; C12N15/12
摘要：
The present invention provides an isolated altered vertebrate telomere repeat binding factor (A-TRFs). Also included are the corresponding nucleic acids that encode the A-TRFs of the present invention, as well as the heterodimers formed by the association of an A-TRF with a TRF. In addition, pharmaceutical compositions containing the A-TRFs for treatment of diseases such as ataxia telangiectasia are also included. Methods of making, purifying and using the A-TRFs of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of the A-TRFs are presented.
公开/授权文献
- USD360181S Portable sun screen for automobile sun roof 公开/授权日：1995-07-11