Invention Grant
US5919408A Process for the production of pseudolatices and micro- or nanoparticles and pharmaceutical preparations containing them 失效
用于制备假胶束和含有微粒或纳米颗粒的药物制剂的方法

Process for the production of pseudolatices and micro- or nanoparticles
and pharmaceutical preparations containing them
Abstract:
The invention relates to a process for the production of pseudolatices or micro- and/or nanoparticles, in which a polymer is crystalline, partially crystalline or amorphous, is selected from cellulose derivatives, poly(meth)acrylates, shellac, polylactides, polylactide/polyglycolide mixtures, polyhydroxy butyric acids or polycyanoacrylates and is heated to a temperature above its glass transition temperature and then high-pressure homogenized in water or an aqueous buffer solution and this suspension is converted, if necessary, into micro- and/or nanoparticles by drying. Medicaments can be worked into the pseudolatices, micro- and/or nanoparticles.
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