Invention Grant
US5919807A Benzothiazoles and benzoxazoles, drugs containing them, their use and
methods of preparing them
失效
苯并噻唑和苯并恶唑，含有它们的药物，其用途和制备方法
- Patent Title: Benzothiazoles and benzoxazoles, drugs containing them, their use and methods of preparing them
- Patent Title (中): 苯并噻唑和苯并恶唑，含有它们的药物，其用途和制备方法
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Application No.: US945612Application Date: 1997-10-28
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Publication No.: US5919807APublication Date: 1999-07-06
- Inventor: Peter Muller , Rudolph Hurnaus , Roland Maier , Michael Mark , Bernhard Eisele , Ralph-Michael Budzinski , Leo Thomas , Gerhard Hallermayer
- Applicant: Peter Muller , Rudolph Hurnaus , Roland Maier , Michael Mark , Bernhard Eisele , Ralph-Michael Budzinski , Leo Thomas , Gerhard Hallermayer
- Applicant Address: DEX Biberach
- Assignee: Dr. Karl Thomae GmbH
- Current Assignee: Dr. Karl Thomae GmbH
- Current Assignee Address: DEX Biberach
- Priority: DEX19517448 19950512
- Main IPC: A23K20/137
- IPC: A23K20/137 ; A61K31/42 ; A61K31/423 ; A61K31/425 ; A61K31/428 ; A61P1/16 ; A61P3/06 ; A61P3/08 ; A61P31/04 ; A61P35/00 ; C07D263/56 ; C07D277/64 ; C07D277/66 ; C07D277/68 ; C07D277/74 ; C07D277/76 ; C07D277/82 ; C07D417/04 ; C07D417/12
Abstract:
The invention relates to benzothiazoles and benzoxazoles of general formula ##STR1## wherein R.sup.1 to R.sup.3, X, Z and n are defined as in claim 1, the enantiomers, diastereomers and salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable properties, particularly an inhibitory effect on cholesterol biosynthesis, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.
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