发明授权
US5919807A Benzothiazoles and benzoxazoles, drugs containing them, their use and
methods of preparing them
失效
苯并噻唑和苯并恶唑，含有它们的药物，其用途和制备方法
- 专利标题： Benzothiazoles and benzoxazoles, drugs containing them, their use and methods of preparing them
- 专利标题（中）： 苯并噻唑和苯并恶唑，含有它们的药物，其用途和制备方法
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申请号： US945612申请日： 1997-10-28
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公开(公告)号： US5919807A公开(公告)日： 1999-07-06
- 发明人: Peter Muller , Rudolph Hurnaus , Roland Maier , Michael Mark , Bernhard Eisele , Ralph-Michael Budzinski , Leo Thomas , Gerhard Hallermayer
- 申请人： Peter Muller , Rudolph Hurnaus , Roland Maier , Michael Mark , Bernhard Eisele , Ralph-Michael Budzinski , Leo Thomas , Gerhard Hallermayer
- 申请人地址： DEX Biberach
- 专利权人： Dr. Karl Thomae GmbH
- 当前专利权人： Dr. Karl Thomae GmbH
- 当前专利权人地址： DEX Biberach
- 优先权： DEX19517448 19950512
- 主分类号： A23K20/137
- IPC分类号： A23K20/137 ; A61K31/42 ; A61K31/423 ; A61K31/425 ; A61K31/428 ; A61P1/16 ; A61P3/06 ; A61P3/08 ; A61P31/04 ; A61P35/00 ; C07D263/56 ; C07D277/64 ; C07D277/66 ; C07D277/68 ; C07D277/74 ; C07D277/76 ; C07D277/82 ; C07D417/04 ; C07D417/12
摘要：
The invention relates to benzothiazoles and benzoxazoles of general formula ##STR1## wherein R.sup.1 to R.sup.3, X, Z and n are defined as in claim 1, the enantiomers, diastereomers and salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable properties, particularly an inhibitory effect on cholesterol biosynthesis, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.
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