发明授权
US5919898A Absorbent for removing interleukins and tumor necrosis factor, and
process for removing the same
失效
用于去除白细胞介素和肿瘤坏死因子的吸收剂及其除去过程
- 专利标题: Absorbent for removing interleukins and tumor necrosis factor, and process for removing the same
- 专利标题(中): 用于去除白细胞介素和肿瘤坏死因子的吸收剂及其除去过程
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申请号: US590599申请日: 1996-01-24
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公开(公告)号: US5919898A公开(公告)日: 1999-07-06
- 发明人: Masaru Nakatani , Shigeo Furuyoshi , Satoshi Takata
- 申请人: Masaru Nakatani , Shigeo Furuyoshi , Satoshi Takata
- 申请人地址: JPX Osaka
- 专利权人: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
- 当前专利权人: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
- 当前专利权人地址: JPX Osaka
- 优先权: JPX7-012082 19950127; JPX7-066565 19950324; JPX7-061182 19950330
- 主分类号: B01D15/08
- IPC分类号: B01D15/08 ; B01J20/32 ; A61K38/00
摘要:
An adsorbent for removing at least one interleukin selected from the group consisting of inerleukin-1, interleukin-2, interleukin-6 and interluekin-8 and/or TNF, which comprises a porous water-insolube carrier and a compound satisfying the value of log P of at least 2.50, in which P is a distribution coefficient in an octanol-water system and being immobilized onto the carrier, a process for removing the above IL(s) and/or TNF by the adsorbent and an adsorber comprising the adsorbent. According to the present invention, IL(s) and TNF in body fluid can be efficiently absorbed using the above-mentioned adsorbent.
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