发明授权
- 专利标题: Condensed heterocyclic compounds, their production and use
- 专利标题(中): 稠合杂环化合物,其生产和使用
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申请号: US554228申请日: 1995-11-08
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公开(公告)号: US5929107A公开(公告)日: 1999-07-27
- 发明人: Hideaki Natsugari , Yasuo Sugiyama , Yoshinori Ikeura
- 申请人: Hideaki Natsugari , Yasuo Sugiyama , Yoshinori Ikeura
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX4-336312 19921216; JPX5-248069 19931004
- 主分类号: C07D209/14
- IPC分类号: C07D209/14 ; C07D209/18 ; C07D209/40 ; C07D307/79 ; C07D307/81 ; C07D307/82 ; C07D333/58 ; C07D333/60 ; C07D333/66 ; A61K31/38
摘要:
Novel compound represented by the formula: ##STR1## wherein ring A, ring B and ring C each stands for an optionally substituted benzene ring; X stands for --NR-- wherein R stands for hydrogen atom or an optionally substituted hydrocarbon group, --O-- or --S--; Y stands for --(CH.sub.2)n-- wherein n denotes 1 or 2 or --NH--; and R.sup.a stands for a hydrogen atom or an optionally substituted hydrocarbon group, provided that when ring C is unsubstituted or substituted only at para-position, ring B is substituted at least at ortho-position or a salt thereof which have an excellent acyl-CoA: cholesterol acyltransferase inhibiting action and cholesterol-lowering activity, their production and medicinal use.
公开/授权文献
- US5191236A System and circuits using Josephson junctions 公开/授权日:1993-03-02
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