A transformable gamma camera includes detectors mounted for circumferential movement with respect to a rotating gantry. The rotating gantry includes radial bores at desired angular positions about the rotating gantry. The stationary gantry includes a docking station such as a bore. A coupling mechanism allows the detectors to be coupled to the bores in the rotating gantry or to the docking station. Each of the detectors is movable radially with respect to the rotating gantry's axis of rotation and tangentially to the imaging region. The gamma camera is readily transformable between 120 degree, orthogonal, and opposed detector configurations; a plurality of aperture sizes can also be defined.