A fluid collection drape for use during surgery includes an impermeable liner, a permeable facing, and a substrate sandwiched between the impermeable liner and the permeable facing. The fluid collection drape is provided in a sterile condition and is sized at about 3 feet by 2.5 feet to substantially cover a width of an operating table. The substrate absorbs greater than about 500 cc of fluid. The fluid collection drape is stored in a sterile state within a package. The substrate has a thickness of about 0.05 inch.