发明授权
- 专利标题: Orphan receptor
- 专利标题(中): 孤儿受体
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申请号: US836620申请日: 1997-05-08
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公开(公告)号: US5958710A公开(公告)日: 1999-09-28
- 发明人: Georg Kuiper , Eva L. K. Enmark , Jan-Ake Gustafsson
- 申请人: Georg Kuiper , Eva L. K. Enmark , Jan-Ake Gustafsson
- 申请人地址: SEX Huddinge
- 专利权人: Karo Bio AB
- 当前专利权人: Karo Bio AB
- 当前专利权人地址: SEX Huddinge
- 优先权: GBX9518272 19950908; GBX9605550 19960315; GBX9607532 19960411; GBX9609576 19960508
- 主分类号: G01N33/50
- IPC分类号: G01N33/50 ; A61K38/00 ; A61K45/00 ; A61P9/00 ; A61P13/08 ; A61P19/10 ; A61P25/28 ; A61P35/00 ; C07K14/705 ; C07K14/72 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12Q1/68 ; G01N33/15 ; G01N33/53
摘要:
This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed "ER.beta." having the amino acid sequence of FIGS. 1, 13A or 14A or substantially the same ambino acid sequence as the amino acid sequence shown in FIGS. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
公开/授权文献
- USD295475S Table 公开/授权日:1988-05-03
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