The present invention provides a multi-piece solid golf ball having excellent durability, excellent shot feel when hitting and good productivity. The present invention relates to a multi-piece solid golf ball which includes a solid core having a inner core and at least one outer core layer formed on the inner core, and a cover covering the solid core, wherein the inner core and outer core are formed from the material obtained by dispersing rubber in an ionomer resin and dynamically vulcanizing it with a vulcanizing agent, wherein the rubber particles dispersed in the ionomer resin have a particle size of not more than 10 .mu.m, the outer core layer has a Shore D hardness of more than that of the inner core by 5 to 30, and a weight ratio of the ionomer resin to the rubber particles is within the range of 95:5 to 30:70.