- 专利标题: Orally administrable opioid formulations having extended duration of effect
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申请号: US508246申请日: 1995-07-27
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公开(公告)号: US5968551A公开(公告)日: 1999-10-19
- 发明人: Benjamin Oshlack , Mark Chasin
- 申请人: Benjamin Oshlack , Mark Chasin
- 申请人地址: CT Norwalk
- 专利权人: Purdue Pharma L.P.
- 当前专利权人: Purdue Pharma L.P.
- 当前专利权人地址: CT Norwalk
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K9/20 ; A61K9/22 ; A61K9/26 ; A61K9/28 ; A61K9/50 ; A61K9/52 ; A61K9/54 ; A61K31/485 ; A61K31/522 ; A61K9/48
摘要:
Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains a plurality of substrates including the opioid analgesic in sustained release form. The substrates have a diameter from about 0.1 mm to about 3 mm.
公开/授权文献
- US5107325A Structure and method of packaging a semiconductor device 公开/授权日:1992-04-21
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