发明授权
- 专利标题: Pyruvate compounds and methods for use thereof
- 专利标题(中): 丙酮酸盐化合物及其使用方法
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申请号: US259941申请日: 1999-03-01
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公开(公告)号: US5968727A公开(公告)日: 1999-10-19
- 发明人: Henri Brunengraber , Catherine Bomont , France David , Peter T. Hallowell
- 申请人: Henri Brunengraber , Catherine Bomont , France David , Peter T. Hallowell
- 申请人地址: OH Cleveland
- 专利权人: Case Western Reserve University
- 当前专利权人: Case Western Reserve University
- 当前专利权人地址: OH Cleveland
- 主分类号: A61P39/02
- IPC分类号: A61P39/02 ; A01N1/02 ; A61K31/215 ; C07C69/716 ; C07C69/738 ; C07C327/34 ; A61K31/22 ; C07C327/06 ; C07C327/20
摘要:
The invention comprises a novel pyruvate compound for the treatment of prevention of reperfusion injury following ischemia, diabetic effects, cholesterol levels, injured organs ethanol intoxication oras s foodstuff. The novel pyruvate compound is particularly a puruvate thiolester, a glucerol-pyruvate ester or a dihydoxyacetone-pyruvate ester.