发明授权
US5972634A Diagnostic assay for Alzheimer's disease: assessment of A.beta.
abnormalities
失效
阿尔茨海默病的诊断测定：Aβ异常的评估
- 专利标题： Diagnostic assay for Alzheimer's disease: assessment of A.beta. abnormalities
- 专利标题（中）： 阿尔茨海默病的诊断测定：Aβ异常的评估
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申请号： US817423申请日： 1997-08-04
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公开(公告)号： US5972634A公开(公告)日： 1999-10-26
- 发明人: Rudolph E. Tanzi , Ashley I. Bush , Robert D. Moir
- 申请人： Rudolph E. Tanzi , Ashley I. Bush , Robert D. Moir
- 申请人地址： MA Boston
- 专利权人： The General Hospital Corporation
- 当前专利权人： The General Hospital Corporation
- 当前专利权人地址： MA Boston
- 主分类号： G01N33/553
- IPC分类号： G01N33/553 ; G01N33/53
摘要：
The disclosed invention relates to assays for detecting and quantifying A.beta. peptide, using solid supports that are coated with heavy metal cations, such as zinc (II) or copper (II) form of a nitriloacetic acid. Further, diagnostic kits are described which are used to carry out the assays of the present invention. An improvement in an assay for detection of A.beta. peptide is suggested which comprises forming a heavy metal cation/solid support complex. The preferred heavy metal cations for this improvement are zinc (II) or copper (II) form of a nitriloacetic acid. Finally, methods and kits for bulk purification of A.beta. peptides from biological fluids are taught.
公开/授权文献
- USD339793S Electrical box connector coupling 公开/授权日：1993-09-28