发明授权
US5977067A Cyclosporin derivatives, their preparation and the pharmaceutical
compositions which contain them
失效
环孢菌素衍生物，它们的制备和含有它们的药物组合物
- 专利标题： Cyclosporin derivatives, their preparation and the pharmaceutical compositions which contain them
- 专利标题（中）： 环孢菌素衍生物，它们的制备和含有它们的药物组合物
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申请号： US69959申请日： 1998-04-30
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公开(公告)号： US5977067A公开(公告)日： 1999-11-02
- 发明人: Michel Evers , Serge Mignani , Jean-Christophe Carry , Bruno Filoche , Georges Bashiardes , Claude Bensoussan , Jean-Christophe Gueguen , Jean-Claude Barriere
- 申请人： Michel Evers , Serge Mignani , Jean-Christophe Carry , Bruno Filoche , Georges Bashiardes , Claude Bensoussan , Jean-Christophe Gueguen , Jean-Claude Barriere
- 申请人地址： FRX Antony Cedex
- 专利权人： Rhone-Poulenc Rorer S.A.
- 当前专利权人： Rhone-Poulenc Rorer S.A.
- 当前专利权人地址： FRX Antony Cedex
- 优先权： FRX9705351 19970430
- 主分类号： C12P21/04
- IPC分类号： C12P21/04 ; A61K38/00 ; A61P31/04 ; A61P31/12 ; A61P31/14 ; A61P31/18 ; A61P37/02 ; C07K7/64 ; A61K37/02 ; C07K5/12
摘要：
Cyclosporin derivatives of formula (I) in which R is H or a radical (Ia) or (Ib) as defined herein; R' is a radical (Ic) or (Id) as defined herein; and R"represents H or OH, with the proviso that R and R" are not simultaneously H, and pharmaceutically acceptable salts thereof, when they exist, are disclosed as useful for the treatment and/or prophylaxis of retrovirus infections. ##STR1##
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