A substitute-heart control apparatus for controlling a substitute heart provided in a living body, including an information obtaining device which non-invasively obtains, from the living body, physical information relating to blood circulation in the living body, and a control device which supplies, to the substitute heart, a control signal to control a cardiac output that is a volume of blood outputted from the substitute heart per unit time, based on the physical information obtained by the information obtaining device, according to a predetermined relationship between cardiac output and physical information.