发明授权
US5981280A Method and constructs for inhibiting protein expression in bacteria
失效
用于抑制细菌中蛋白质表达的方法和构建体
- 专利标题： Method and constructs for inhibiting protein expression in bacteria
- 专利标题（中）： 用于抑制细菌中蛋白质表达的方法和构建体
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申请号： US769945申请日： 1996-12-19
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公开(公告)号： US5981280A公开(公告)日： 1999-11-09
- 发明人: Li Fang , Weining Jiang , Masanori Mitta , Masayori Inouye
- 申请人： Li Fang , Weining Jiang , Masanori Mitta , Masayori Inouye
- 申请人地址： NJ Piscataway
- 专利权人： The University of Medicine and Denistry of New Jersey
- 当前专利权人： The University of Medicine and Denistry of New Jersey
- 当前专利权人地址： NJ Piscataway
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12N1/21 ; C12N15/113 ; C12N15/63 ; C12N15/67 ; C12P21/02 ; C12Q1/02 ; C07H21/02 ; C07H21/04
摘要：
A method of inhibiting the translation of bacterial mRNA is disclosed, which method comprises overexpressing in a bacterium an mRNA which contains a sequence which is complementary to the anti-downstream box region of the 16S rRNA. RNA and DNA constructs for the overexpression of the mRNA of the invention are disclosed.
公开/授权文献
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