发明授权
- 专利标题: Pyrazole derivatives and processes for the preparation thereof
- 专利标题(中): 吡唑衍生物及其制备方法
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申请号: US930904申请日: 1997-10-03
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公开(公告)号: US5981533A公开(公告)日: 1999-11-09
- 发明人: Peter Traxler , Pascal Furet , Guido Bold , Jorg Frei , Marc Lang
- 申请人: Peter Traxler , Pascal Furet , Guido Bold , Jorg Frei , Marc Lang
- 申请人地址: CHX Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CHX Basel
- 优先权: CHX937/95 19950403; CHX421/96 19960216
- 主分类号: C07D231/38
- IPC分类号: C07D231/38 ; A61K31/505 ; A61P35/00 ; A61P43/00 ; C07D487/04
摘要:
4-Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula I ##STR1## wherein the symbols are as defined in claim 1, and intermediates for their manufacture are described.The compounds of formula I inhibit especially the tyrosine kinase activity of the receptor for epidermal growth factor and can be used, for example, in the case of epidermal hyperproliferation (psoriasis) and as anti-tumor agents.
公开/授权文献
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