发明授权
US5989855A Bile acid converting microorganism and process for preparing bile acid
失效
胆汁酸转化微生物和制备胆汁酸的方法
- 专利标题： Bile acid converting microorganism and process for preparing bile acid
- 专利标题（中）： 胆汁酸转化微生物和制备胆汁酸的方法
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申请号： US155232申请日： 1998-09-29
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公开(公告)号： US5989855A公开(公告)日： 1999-11-23
- 发明人: Akio Okamura , Hiroyuki Matsui
- 申请人： Akio Okamura , Hiroyuki Matsui
- 申请人地址： JPX Tokyo
- 专利权人： Tokyo Tanabe Company Limited
- 当前专利权人： Tokyo Tanabe Company Limited
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX8-077945 19960329
- 主分类号： C12P33/06
- IPC分类号： C12P33/06 ; C12N1/14
摘要：
A microorganism having a capability of introducing a 7.beta.-hydroxyl group into a 7-unsubstituted bile acid, and a process for preparing a bile acid having a 7.beta.-hydroxyl group characterized by bringing the above microorganism into contact with a 7-unsubstituted bile acid to convert the acid to a bile acid having a 7.beta.-hydroxyl group. The process permits ursodeoxycholic acid useful as a cholagogue and intermediates therefor to be efficiently prepared.
公开/授权文献
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