发明授权
US5990119A 1,4,4-(trisubstituted)cyclohexane monomers and related compounds
失效
1,4,4-（三取代）环己烷单体和相关化合物
- 专利标题： 1,4,4-(trisubstituted)cyclohexane monomers and related compounds
- 专利标题（中）： 1,4,4-（三取代）环己烷单体和相关化合物
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申请号： US605033申请日： 1997-06-23
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公开(公告)号： US5990119A公开(公告)日： 1999-11-23
- 发明人: Siegfried B. Christensen, IV , Joseph M. Karpinski , M. Dominic Ryan , Paul E. Bender
- 申请人： Siegfried B. Christensen, IV , Joseph M. Karpinski , M. Dominic Ryan , Paul E. Bender
- 申请人地址： PA Philadelphia
- 专利权人： SmithKline Beecham Corporation
- 当前专利权人： SmithKline Beecham Corporation
- 当前专利权人地址： PA Philadelphia
- 主分类号： C07D213/30
- IPC分类号： C07D213/30 ; A61K31/435
摘要：
Novel compounds of formula I are described herein. These compounds inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV.
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