发明授权
US5990155A Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl
protease
失效
含有天冬氨酰蛋白酶磺酰胺抑制剂的含氧杂环
- 专利标题： Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl protease
- 专利标题（中）： 含有天冬氨酰蛋白酶磺酰胺抑制剂的含氧杂环
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申请号： US977365申请日： 1997-11-24
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公开(公告)号： US5990155A公开(公告)日： 1999-11-23
- 发明人: Roger D. Tung , Govinda Rao Bhisetti
- 申请人： Roger D. Tung , Govinda Rao Bhisetti
- 申请人地址： MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： MA Cambridge
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; A61K31/34 ; A61K31/341 ; A61K31/357 ; A61P31/12 ; A61P43/00 ; C07D307/20 ; C07D309/12 ; C07D317/24 ; C07D319/06 ; C07D493/04 ; A61K31/35 ; C07D311/00
摘要：
The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention.
公开/授权文献
- US5272116A Method for pattern defect correction of a photomask 公开/授权日：1993-12-21
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