A highly reliable solid-state image pickup device with one- or two-dimensionally arranged connecting portions, capable of avoiding corrosion of wirings resulting from chipping of the substrates and eliminating image defect, is achieved by arranging plural substrates, each bearing a plurality of image taking elements, in a planar manner on a supporting substrate and filling the connecting portions of thus arranged substrates with an organic or inorganic material, of which content in chlorine or in each of sodium and potassium does not exceed 200 ppm.