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US5994559A Synthesis of monatin-A high intensity natural sweetener 失效
monatin-A高强度天然甜味剂的合成

Synthesis of monatin-A high intensity natural sweetener
摘要:
The high intensity natural sweetener monatin, an .alpha.-amino acid (1) is synthesized from readily available starting materials. Regiospecific ring opening of epoxide (9) with indole magnesium bromide yields lactone (11). Amination of (11) followed by saponification yields Monatin.
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