A mechanical counter pressure glove includes an elastic supportive material and a plurality of pre-pressurized bladders in the supportive material. At least one of the bladders is configured to match a configuration of a palm of a hand. The bladders may also be configured to match other parts of the hand, such as the dorsum and fingers. Each of the bladders is pre-pressurized to match a tissue pressure in the user's hand prior to the glove being worn. Thereby, the bladders are self contained and omit the need for a constant available supply of gas pressure from an external source.