发明授权
- 专利标题： In vitro activation of cytotoxic T cells
- 专利标题（中）： 细胞毒T细胞的体外活化
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申请号： US103486申请日： 1998-06-24
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公开(公告)号： US6001365A公开(公告)日： 1999-12-14
- 发明人: Per A. Peterson , Michael Jackson , Pierre Langlade-Demoyen
- 申请人： Per A. Peterson , Michael Jackson , Pierre Langlade-Demoyen
- 申请人地址： CA La Jolla
- 专利权人： The Scripps Research Institute
- 当前专利权人： The Scripps Research Institute
- 当前专利权人地址： CA La Jolla
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P31/00 ; A61P37/02 ; A61K39/385 ; A61K38/02 ; C12N5/06
摘要：
The present invention relates to a rational, elegant means of producing, loading and using Class I molecules to specifically activate CD8 cells in vitro, and their therapeutic applications in the treatment of a variety of conditions, including cancer, tumors or neoplasias, as well as viral, retroviral, autoimmune, and autoimmune-type diseases. The present invention also relates to vectors, cell lines, recombinant DNA molecules encoding human .beta.2 microglobulin or Class I MHC molecules in soluble and insoluble form, and methods of producing same.
公开/授权文献
- USD425825S Cargo box 公开/授权日：2000-05-30
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