发明授权
- 专利标题: Human gamma interferon antagonist/agonist screen
- 专利标题(中): 人γ干扰素拮抗剂/激动剂筛选
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申请号: US959509申请日: 1992-10-09
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公开(公告)号: US6001560A公开(公告)日: 1999-12-14
- 发明人: Herinder K. Lonial , Satwant K. Narula , Paul J. Zavodny
- 申请人: Herinder K. Lonial , Satwant K. Narula , Paul J. Zavodny
- 申请人地址: NJ Kenilworth
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 当前专利权人地址: NJ Kenilworth
- 主分类号: C12N5/10
- IPC分类号: C12N5/10 ; C07K14/61 ; C07K14/74 ; C07K16/26 ; C12N15/09 ; C12N15/85 ; C12P21/02 ; C12Q1/02 ; C12Q1/68 ; C12R1/91 ; G01N33/569 ; C07H21/09
摘要:
Stably-transformed human cell lines containing a human gamma interferon-responsive human HLA-DR.alpha. promoter operatively linked to a reporter gene are provided. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human gamma interferon.
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