- 专利标题： Substituted pyridines as selective cyclooxygenase-2 inhibitors
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申请号： US181887申请日： 1998-10-29
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公开(公告)号： US6001843A公开(公告)日： 1999-12-14
- 发明人: Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Yves Gauthier
- 申请人： Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Yves Gauthier
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/444 ; A61K31/655 ; C07D213/04 ; C07D213/22 ; C07D213/26 ; C07D213/34 ; C07D213/36 ; C07D213/44 ; C07D213/54 ; C07D213/61 ; C07D213/65 ; C07D213/75 ; C07D213/80 ; C07D213/85 ; C07D213/89 ; A61K31/535 ; C07D211/70 ; C07D211/72 ; C07D211/78
摘要：
The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
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