发明授权
US6004761A Method for detecting cancer using monoclonal antibodies to new mucin
epitopes
失效
使用针对新的粘蛋白表位的单克隆抗体检测癌症的方法
- 专利标题: Method for detecting cancer using monoclonal antibodies to new mucin epitopes
- 专利标题(中): 使用针对新的粘蛋白表位的单克隆抗体检测癌症的方法
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申请号: US459025申请日: 1995-06-02
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公开(公告)号: US6004761A公开(公告)日: 1999-12-21
- 发明人: Peter S. Linsley , Diane Horn , Joseph P. Brown
- 申请人: Peter S. Linsley , Diane Horn , Joseph P. Brown
- 申请人地址: FRX Paris
- 专利权人: Sanofi
- 当前专利权人: Sanofi
- 当前专利权人地址: FRX Paris
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K16/30 ; G01N33/574 ; G01N33/53
摘要:
Novel hybridoma cell lines producing monoclonal antibodies reactive with purified mucin antigens from normal and tumor sources are generated using mucins, including purified mucins from tumor sources. Epitopes on mucin antigens from normal and tumor sources are demonstrated to be distinct, using these new antibodies. The antibodies may be useful alone or in combination, in the diagnosis and treatment of cancer including malignancies of the breast and lung.
公开/授权文献
- US5044814A Clamping band 公开/授权日:1991-09-03
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