发明授权
- 专利标题: Use of anhydrovinblastine
- 专利标题(中): 使用脱氢长春花碱
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申请号: US690195申请日: 1996-07-26
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公开(公告)号: US6011041A公开(公告)日: 2000-01-04
- 发明人: Bruce Schmidt , James Kutney , Lawrence Mayer
- 申请人: Bruce Schmidt , James Kutney , Lawrence Mayer
- 申请人地址: Vancouver
- 专利权人: University of British Columbia
- 当前专利权人: University of British Columbia
- 当前专利权人地址: Vancouver
- 主分类号: C07D519/04
- IPC分类号: C07D519/04 ; A61K31/33 ; A61K31/485 ; A61K43/42
摘要:
The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an antineoplastic agent in the therapeutic treatment of cancer. Specifically, the treatment of lymphoma with 3',4'-anhydrovinblastine is disclosed.
公开/授权文献
- US5204225A Process for producing negative images 公开/授权日:1993-04-20
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