发明授权
US6015805A 17.beta.-nitro-11.beta.-arylisteroids and their derivatives having
agonist or antagonist hormonal properties
有权
17β-硝基-11β-芳醚甾族化合物及其衍生物具有激动剂或拮抗剂的激素特性
- 专利标题： 17.beta.-nitro-11.beta.-arylisteroids and their derivatives having agonist or antagonist hormonal properties
- 专利标题（中）： 17β-硝基-11β-芳醚甾族化合物及其衍生物具有激动剂或拮抗剂的激素特性
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申请号： US317945申请日： 1999-05-25
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公开(公告)号： US6015805A公开(公告)日： 2000-01-18
- 发明人: C. Edgar Cook , John A. Kepler , Rupa S. Shetty , Gary S. Bartley , David Yue-wei Lee
- 申请人： C. Edgar Cook , John A. Kepler , Rupa S. Shetty , Gary S. Bartley , David Yue-wei Lee
- 申请人地址： NC Research Triangle Park
- 专利权人： Research Triangle Research North Carolina
- 当前专利权人： Research Triangle Research North Carolina
- 当前专利权人地址： NC Research Triangle Park
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; A61K31/58 ; A61K45/06 ; A61P15/00 ; A61P35/00 ; A61P43/00 ; C07J41/00 ; C07J43/00
摘要：
The invention is directed to 11.beta.-arylsteroids of formula II: ##STR1## wherein R.sup.1, R.sup.6, R.sup.8, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
公开/授权文献
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