发明授权
- 专利标题: Methods of treating or preventing interstitial cystitis
- 专利标题(中): 治疗或预防间质性膀胱炎的方法
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申请号: US125952申请日: 1998-08-25
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公开(公告)号: US6017930A公开(公告)日: 2000-01-25
- 发明人: Smriti Iyengar , Mark A. Muhlhauser , Karl B. Thor
- 申请人: Smriti Iyengar , Mark A. Muhlhauser , Karl B. Thor
- 申请人地址: IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: IN Indianapolis
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/445
摘要:
This invention provides methods for the treatment or prevention of interstitial cystitis or urethral syndrome in a mammal which comprise administering to a mammal in need thereof an effective amount of a compound of formula (I), where R.sup.1 and R.sup.2 are independently selected from the group consisting of hydrogen, methyl, methoxy, chloro, and trifluoromethyl, with the proviso that no more than one of R.sup.1 and R.sup.2 can be hydrogen; and Y is (1), (2), (3), (4), (5), (6), N--R.sup.a, or CH--NR.sup.b R.sup.c, where R.sup.a, R.sup.b, and R.sup.c are independently selected from the group consisting of hydrogen and C.sub.1 -C.sub.6 alkyl; or a pharmaceutically acceptable salt or solvate thereof. ##STR1##
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