发明授权
- 专利标题: Polymeric microporous film coated subcutaneous implant
- 专利标题(中): 聚合微孔薄膜皮下植入
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申请号: US990367申请日: 1997-12-15
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公开(公告)号: US6022554A公开(公告)日: 2000-02-08
- 发明人: Jung-Chung Lee , Shamim Pushpala , Charles E. Lee
- 申请人: Jung-Chung Lee , Shamim Pushpala , Charles E. Lee
- 申请人地址: NJ Madison
- 专利权人: American Home Products Corporation
- 当前专利权人: American Home Products Corporation
- 当前专利权人地址: NJ Madison
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/28 ; A61K9/50 ; A61F2/00 ; A61F2/10
摘要:
This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a biologically active agent to provide a release of the active agent at a constant rate over a prolonged period of time. The pore forming agent is used in the formulation of the invention in the amount effective to regulate the release of a biologically active compound at a desired rate. Preferably, the effective amount of the pore forming agent provides long term delivery of the active agent. The invention also provides an improved implant for the sustained administration of a biologically active compound suitable for subcutaneous implantation. The invention also relates to methods for making and using the formulation and the implant of the invention.
公开/授权文献
- US5366480A Synthetic elastomeric buttressing pledget 公开/授权日:1994-11-22
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