发明授权
- 专利标题： Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies
- 专利标题（中）： 含喹唑啉酮的药物组合物，用于预防新血管形成和治疗恶性肿瘤
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申请号： US797703申请日： 1997-02-11
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公开(公告)号： US6028075A公开(公告)日： 2000-02-22
- 发明人: Mark Pines , Israel Vlodavsky , Arnon Nagler , Hua-Quan Miao
- 申请人： Mark Pines , Israel Vlodavsky , Arnon Nagler , Hua-Quan Miao
- 专利权人： Pines; Mark,Vlodavsky; Israel,Nagler; Arnon,Miao; Hua-Quan
- 当前专利权人： Pines; Mark,Vlodavsky; Israel,Nagler; Arnon,Miao; Hua-Quan
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; A61K31/517 ; A61P35/00 ; A61P43/00 ; A61K31/505
摘要：
The invention provides a composition for attenuating neovascularization and treating malignancies, including a pharmaceutically effective amount of a compound having a formula: ##STR1## wherein: R.sub.1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy;R.sub.2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, andR.sub.3 is a member of the group consisting of hydrogen and lower alkenoxy carbonyl;as active ingredient therein, in combination with a pharmaceutically acceptable carrier.
公开/授权文献
- US5156258A Scraper-chain conveyors for use in mineral mining 公开/授权日：1992-10-20
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